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Minor side effects rarely require discontinuation

Visible changes in weight may require several additional weeks

However, when this mechanism is replicated using drugs such as semaglutide or tirzepatide, a single injection on day one leads to GLP-1 levels that are significantly higher than normal levels, remaining elevated for a week before dropping again, requiring another injection

Trimix Injections Trimix , an intracavernosal injection containing alprostadil, papaverine, and phentolamine, offers reliable results for severe ED but comes with higher procedural risks: Pain at the injection site Risk of priapism (prolonged erection) Fibrosis or scarring with repeated use PT-141 , administered subcutaneously rather than directly into penile tissue, avoids these complications entirely