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Furthermore, older patients may have a condition called vascular depression, meaning depression related to a decrease in the blood supply to areas of the brain involved in mood or mood-related functions

The 12 mg dose had higher gastrointestinal event rates and higher discontinuation due to adverse events than lower doses, emphasizing the need to balance efficacy with tolerability

These findings suggest that GLP-1RAs could represent a promising pharmacological approach for treating asthma in obese patients [47]

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