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Furthermore, the current status of clinical trials (collected from clinicaltrials.gov) of the N-to-B delivery systems for several CNS disorders/diseases, including proteins and peptides, was discussed by Pandey et al
ROS as double-edged swords in cancer Several noncancer cells associate with tumors: among these, cancer-associated fibroblasts (CAFs), particularly represented in the tumor microenvironment (TME), actively contribute to the regulation of tumor homeostasis, promoting tumor progression and the invasion of cancer cells
We are all exposed to toxins in our environment such as car exhaust, charred foods, pesticides, cleaning chemicals, radiation from the sun, and trace amounts of heavy metals in our food
To counteract this oxidative damage induced by paraquat, and MPTP, astrocytes seem to protect dopaminergic neurons by increasing expression of antioxidant molecules, such as heme oxigenase1 (EC 1.14.99.3), glutathione S-transferase P (EC 2.5.1.18) and glutathione [90,91]
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