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pneumoniae remains a significant public health concern, with reports indicating it is responsible for over 1.2 million deaths annually, primarily affecting young children and the elderly ( Furthermore, the increasing antibiotic resistance of this pathogen poses substantial challenges to the treatment of invasive pneumococcal diseases

An unanswered question, however, is whether intensive behavioral therapy (BT) with an initial low-calorie and meal-replacement diet or specialist cognitive behavior therapy (CBT) for obesity are still necessary to help the patients achieve the long-term weight loss obtained by semaglutide and tirzepatide (257)

The exact dosing regimen and instructions for administration will be provided by a healthcare provider based on the patients individual needs and the specific formulation of tirzepatide

Khan S, et al