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A prospective cohort study involving 266 elderly adults treated with epithalamin (the parent compound from which Epithalon was derived) over 2-3 years with subsequent 4-5 year follow-up demonstrated mortality reduction of 28% overall, with a 2-fold decrease in cardiovascular disease-specific mortality

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However, in HCT116 cells, L-BSO was not cytotoxic even at concentrations as high as 3.2 mmol L 1 (Supplementary Fig

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