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To improve corneal residence time, penetration, and targeted administration of natural compounds, future research should use in situ gels, nanoparticle-based carriers (liposomes, polymeric NPs), and contact lens drug delivery

Literature context belongs in the background section

Ibuprofen is known to worsen these symptoms and increase the risk of inflammatory bowel complications

These findings suggest that Gln metabolism should be understood more appropriately as a metabolic network node, whose effects depend on nutrient availability, mitochondrial functional status, and its mode of coupling with other metabolic pathways, such as glycolysis and TCA cycle interruption and anaplerosis