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Some women notice very little change, while others experience significant differences in their cycle

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Among the 77 infants tested at 6 weeks of age, the median blood vitamin B 12 level was 199 pmol/L (270 ng/L) in the supplemented group and 139 pmol/L (188 ng/L) in the placebo group.[23] Sixty-eight pregnant women in Bangladesh received 250 mcg oral vitamin B 12 capsules or placebo once daily beginning during their first trimester of pregnancy and continuing until 3 months postpartum

Concentrations reported in published preclinical animal studies vary widely by model, route, and endpoint, and they are not dosing recommendations