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The TP53 gene codes for a tumor-suppressor protein known to trigger cell cycle arrest, apoptosis, or senescence in response to a variety of cellular dysfunctions, including DNA damage, oncogene activation, and hypoxia [50]

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One function of the N-terminal fragment is to form membrane nanoscopic pores, leading to cell swelling and proinflammatory cytokine release

Gradually increasing your dose helps your physician identify the appropriate concentration of the medication for your needs, while also mitigating any side effects that may occur as you adjust to the medicine