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Agreeably, we could only detect a non-significant tendency for reduced -arrestin 2 recruitment in our triple AA phospho-null mutant receptor despite significantly reduced internalisation in response to GLP-1 stimulation, with this effect more likely ascribed to the observed reduction in GRK2 recruitment, in agreement with a previous report highlighting GRK expression as required for GLP-1R internalisation (4)

Mar 16, 2026 Of the 461,000 GLP-1 users studied in one retrospective analysis, 12.7% developed a new nutritional deficiency within just six months

This treatment is especially popular among busy professionals, athletes, and anyone with a demanding lifestyle

Further zooming into the impacts of GLP-1 on food consumption, a Morgan Stanley Research report provides interesting early insights on how GLP-1 users eating habits are changing (see figure below)