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Rapid entry of glucose through solute carrier family 2 (facilitated glucose transporter), member 2 (GLUT2) for rodents and solute carrier family 2 (facilitated glucose transporter), member 1 (GLUT1) for humans is followed by phosphorylation of glucose which increases glycolytic flux, producing pyruvate as the terminal product of the pathway [3]

PMID: 40500345 Biomater Res A Multimodal Energy-Depletion Strategy for Cooperative Tumor Metabolism Regulation in Enhanced Cancer Therapy