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In an experimental study performed in 5/6 nephrectomized normo- and hyperuricemic rats, febuxostat protected against renal damage, and prevented proteinuria, preserving vessel morphology and glomerular pressure, thus it prevents progression of CKD independently of its effect on UA.46 In the FOCUS47 extension study, 116 patients treated with febuxostat were followed for 5 years

Front Psychiatry 11:181 Kwateng WN (2025) Small Intestinal Bacterial Overgrowth (SIBO) Statistics: Global and US Overview, Types, Trends, and Complications Kyei-Baffour VO, Vijaya AK, Burokas A, Daliri EB-M (2025) Psychobiotics and the gut-brain axis: advances in metabolite quantification and their implications for mental health

Conclusions The whole range of primary genetic astrocytopathies is yet to be fully characterised

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