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There were no significant differences in free cysteine levels in breast milk between the 1.5 grams L-cysteine and the groups receiving no supplement and 3 grams L-cysteine ( p =0.05, p =0.36, respectively)

However, few data exist that demonstrate different treatment outcomes in phenotypically defined patients, with the exception of cystoscopic treatment of Hunner lesions (see Management of Interstitial Cystitis/Bladder Pain Syndrome )

Furthermore, combination therapy was associated with a mean 3.22 kg reduction in body weight and did not increase the risk of hypoglycaemia (RR 0.99) versus other therapies