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The overlap of primary studies is inevitable in multiple systematic reviews

But the specifics of this process - including how much time pharmacies have to exhaust existing inventory, whether existing patient prescriptions can continue to be filled, and how shortage status applies to specific dosage forms versus the drug as a whole - have been the subject of significant legal debate and litigation

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It is reported that angiogenesis and its major regulator VEGF are controlled by multiple transcription factors in the tumor microenvironment, including androgen receptors [56] and estrogen receptors [5, 57]