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Reduced Reward Sensitivity: By dampening the brain's response to highly rewarding stimuli, GLP-1 RAs might help individuals feel less driven by immediate gratification, which can be beneficial in managing conditions like depression and substance use disorders

Others find that evening dosing helps control nighttime snacking, which is a significant calorie source for many people

However, the study included a small number of participants and a shorter follow up time of only 48 weeks compared to other RCTs studying GLP-1 agonists

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