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Compounds that serve as antioxidants, such as enzymes (e.g., Cu/Zn-superoxide dismutase [SOD], extracellular SOD, Mn-SOD, glutathione peroxidase, catalase) and low-molecular-weight antioxidants (e.g., uric acid and ascorbate), are induced early after ischemia and trauma

Because tirzepatide also acts on the GLP-1 pathway, it slows gastric emptying in much the same way, so the gut side effects tend to look familiar