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On the basis of its clinical features, four forms of breast cancer have been identified: ductal carcinoma in situ (DCIS), invasive ductal carcinoma (IDC), inflammatory breast cancer (IBC), and metastatic breast cancer

Tesamorelin may increase IGF-1 to supranormal levels, which requires monitoring

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4.7 Vascular niche and endothelial cell signaling In addition to angiogenesis, endothelial cells play an important role in the regulation of breast cancer progression by forming a vascular niche which promotes the survival, stemness, and metastatic spread of tumor cells (127)