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This neurodegeneration is accompanied by the formation of characteristic Lewy bodies, which are intracellular inclusions composed largely of aggregated and misfolded -synuclein ( This degeneration of dopaminergic neurons is strongly linked to the generation of reactive oxygen species and oxidative stress as well as mitochondrial dysfunction, neuroinflammation, and aging ( The interplay between mitochondrial function and GSH is especially critical in PD

[DOI] [PMC free article] [PubMed] 72.Ghashghaeinia M, Cluitmans JC, Akel A, Dreischer P, Toulany M, Kberle M, et al

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