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Safety concerns with IV glutathione for skin lightening: Side effects including skin rashes, abdominal pain, thyroid dysfunction, liver dysfunction, kidney dysfunction, and possible kidney failure have been reported with intravenous glutathione injections [60]

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In a frequently cited 1999 rat wound study in the Journal of Investigative Dermatology, topical Thymosin Beta-4 was associated with a 42% increase in reepithelialization at four days and as much as 61% at seven days compared with saline controls, alongside increased angiogenesis