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Medication interactions : Certain medications can interfere with weight loss efforts, including some antidepressants (particularly paroxetine, mirtazapine), antipsychotics (especially olanzapine, quetiapine), mood stabilizers (valproate), antiepileptics (gabapentin, pregabalin), corticosteroids, beta-blockers, and diabetes medications (insulin, sulfonylureas)

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Requires adequate hydration dehydration reduces filtration rate and concentrates toxins

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