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The researchers also conducted RNA-sequencing, which apparently pointed to reduced activity of pathways involved in ECMreceptor interaction and focal adhesion, alongside lower levels of key ECM proteins such as fibronectin, tenascin C, laminin, thrombospondin-2, and Hmmr

In summary, despite a small increase in missed trypsin cleavages, in-cell LiP-MS generated data of similar quality to the established in-lysate method

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6.1 Biomarkers of ferroptosis in ARDS The identification of reliable biomarkers is critical for diagnosing ferroptosis-driven ARDS, stratifying patients for treatment, and monitoring therapeutic responses