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expect minimal GI effects | | 58 | **2mg** | Appetite suppression becomes noticeable | | 912 | **4mg** | Most users experience meaningful weight loss | | 1316 | **6mg** | Escalate only if tolerating 4mg well | | 1720 | **8mg** | Phase 2 trial's mid-high dose | | 21+ | **12mg** | Maximum studied dose

Managing Cost and Access for Long-Term GLP-1 Therapy One of the most significant barriers to long-term GLP-1 use has been cost, particularly for patients without insurance coverage

Most insurance plans deny coverage for Ozempic prescribed for weight loss alone, as they typically require a diabetes diagnosis or extensive documentation of failed dieting

Available from: [7] Mounjaro Cost Information | With or Without Insurance |Mounjaro (tirzepatide) injection [Internet]