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SURMOUNT-2, in participants with type 2 diabetes, showed 12.8% and 14.7% weight loss at 10mg and 15mg respectively

Macro vascular complications are still the primary cause of death in patients with T2DM.Glucagon like peptide-1 receptor agonists (GLP1-RAs) are a new class of Injectable Anti-diabetes Agents (IADA) that provides blood glucose control with weight reduction ability, systolic blood pressure reduction and a noticeable improvement of lipid profile

10.1056/NEJMoa2108269 28 GilbertM

The rates of adverse events, predominantly hypoglycemia, were lower in the standard-therapy group than in the intensive-therapy group