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In practice, it seems better to tailor the choice to different patients, depending on the preference of the route of administration (oral vs injectable), the presence of intolerance or side-effects, and contraindications

Alarmingly, this metabolic fallout is not restricted to individuals with pre-existing obesity or diabetes

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Notably, this review synthesizes the molecular mechanisms through which exercise mitigates atherosclerosis, encompassing the regulation of exercise-induced factor expression, promotion of iWAT browning and BAT activation, elevation of blood lactate concentration to facilitate lactylation modification, and suppression of diverse cell death pathways