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Materials and methods Animal We crossed Adiponectin - Cre (C57BL/6 background) mice with Ssu72 flox/flox (Ssu72 WT, C57BL/6 background) mice to generate adipocyte-specific Ssu72 knockout (Ssu72 flox/flox

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Whereas GLP-1 decreases plasma glucose levels by exerting insulinotropic effects, glucagon stimulates hyperglycemia by enhancing hepatic glucose output

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