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The side effects typically subside over time as the patient gets used to taking the medication and their body adjusts to the dosage

Across the SLD spectrum, GLP-1 RAs demonstrated modest but directionally consistent improvements in liver enzyme profiles (alanine aminotransferase [ALT] and aspartate aminotransferase [AST]), with 4 of the 7 ALT outcome estimates showing significant reductions, and 4 of the 9 AST outcome estimates showing significant reductions

[sources 11] JunD, a transcription factor, and G9a, a histone methyltransferase enzyme, both oppose the function of FosB and inhibit increases in its expression

Fever: Present with infections, absent with histamine responses