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It is well known that the main anti-inflammatory effect from chronic PE derives from the acute large release of muscle IL-6 (during acute exercise bouts) to the bloodstream, which exerts a paracrine effect in several tissues and organs such as the brain, bones, and digestive tract (Ellingsgaard et al., 2019)

which focused on the long-term efficacy of lycopene rather than its comparison with other therapeutic reagents (Kumar et al., 2007

Just a side note, BPC-157 stands for Body Protection Compound

Preparation and characterization of solid lipid nanoparticles encapsulated noscapine and evaluation of its protective effects against imiquimod-induced psoriasis-like skin lesions