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eating small, low-fat meals and staying hydrated can help Vomiting less common but possible, especially if dietary advice is not followed Diarrhoea or constipation changes in bowel habit are frequently reported during dose initiation Reduced appetite while therapeutically desirable, this can occasionally lead to insufficient caloric intake if meals are skipped entirely Injection site reactions mild redness, bruising, or discomfort at the injection site Fatigue or dizziness some individuals feel lightheaded, particularly if food intake is significantly reduced These side effects are generally mild to moderate in severity and tend to improve as the body adjusts to the medication over the first few weeks

Retatrutide vs Tirzepatide Side Effects Both medications appear to share many similar side effects because they affect overlapping hormone systems

Zarghami also developed the kind of muscle weakness that would be expected only after running a marathon

The first is the PI3K-Akt pathway, a molecular cascade that governs cell survival, growth, and the uptake of glucose in response to insulin