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I did notice that both 5 Axis and MD Exam were in the email subject line, which could lead to some confusion

Brodows, M.D Dennis D Kim, MD The diabetes epidemic continues to grow worldwide, with the number of patients increasing each year due to risk factors of obesity and sedentary lifestyle.[1] In addition, patients with type 2 diabetes have a 2-4 fold increased risk of cardiovascular disease, including heart disease and stroke, resulting in a higher incidence of morbidity and mortality, compared to those individuals without diabetes.2 A higher incidence of microvascular complications, which includes renal disease, retinal disease and neuropathic disease, have also been reported

Hydroxyproline comes from collagen breakdown (or from dietary collagen consumption)

Sources Catanese, Lisa