If you notice persistent nail abnormalities lasting more than 46 weeks, particularly when accompanied by other symptoms such as fatigue, pallor, shortness of breath, pins and needles, or cognitive changes, you should consult your GP for proper assessment
Laboratory studies inclusive of plasma acetaminophen and plasma salicylate levels (if there is any concern of a coingestant) should be obtained, in addition to a complete blood count, electrolytes, coagulation studies (prothrombin time and partial thromboplastin time), liver transaminase (alanine transaminase and aspartate transaminase) levels, and bilirubin level
Most reports describe first changes at weeks 4 to 6, with peak effect at 8 to 12 weeks
Timing Baseline Marker Fasting glucose Why it matters Gives a current glucose snapshot when appetite, intake, and medication needs change