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The MHRA ( Medicines and Healthcare products Regulatory Agency ) has two main application procedures: Simple Reclassification : This is a straightforward and quick procedure based on an analogous product (a medicinal product already on the UK market with the same active ingredient, route of administration, use, and a similar or higher strength/dosage)

however, a progressive decline was observed after 10 weeks

[DOI] [PMC free article] [PubMed] [Google Scholar] Gil L, Siems W, Mazurek B, Gross J, Schroeder P, Voss P, Grune T

A further safety concern highlighted by the ADDF is the possibility that synthetic or isolated preparation of epithalon may constrain impurities and pose a safety risk [1]