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In the semaglutide group, no patients in STEP 3 or STEP 4 and 1% of patients in STEP 1 progressed to diabetes while in the placebo group, no patients in STEP 4, 1% of patients in STEP 3, and 3% of patients in STEP 1 progressed to diabetes

The two drugs work differently

Mice were randomly assigned to treatment and control groups

After short-term repeated exposures, dominant lethals were induced in mice at intraperitoneal doses from 40 mg/kg body weight, given over a period of 3 months, 5 times per week (Lyarskii et al., 1983) and at vapour exposures from 460 mg/m 3 , for 6 h/day, 5 days per week, over 11 weeks (Generoso et al., 1983)