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Its unique mechanism lies in bypassing the traditional dopamine pathway and directly acting as a melanocortin receptor agonist, precisely activating MC4R and MC1R in the central nervous system

Youre most likely to notice side effects when you first start taking Wegovy or Mounjaro, or when you increase your dose, but they tend to resolve over time as your body adjusts to treatment

Commonly reported side effects include: Gastrointestinal symptoms nausea, vomiting, diarrhoea, and constipation are the most frequently reported adverse effects, particularly during dose escalation

The UK Medicines and Healthcare products Regulatory Agency concluded that the available evidence did not establish a causal relationship between the GLP-1 receptor agonists it assessed and depression, suicidal behaviour or self-injury