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Although semaglutide is not specifically approved for RA, some people with RA have started using it off-label to see if it might help with their symptoms, especially pain and inflammation

Both medications share similar GLP-1 class side effects, primarily nausea and GI symptoms during dose escalation that typically resolve within weeks

One study showed that giving intravenous glutathione helped with symptoms like tremors and stiffness

Some conditions can make you eligible for Semaglutide GLP-1 with a BMI of 27 such as polycystic ovary syndrome (PCOS) as this can make it difficult for women to lose weight with diet and exercise, those who have high blood pressure, and those that have high cholesterol