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Not only is ghrelin linked to obesity and diabetes, but studies have also shown a role in stress, anxiety, depression, and more (Lutter et al., 2008

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Studies have found that deficiencies in the leucine transporter SLC7a5 lead to insufficient leucine uptake, which limits T cell activation and Th17 cell differentiation by suppressing the expression of c-Myc and the activity of mTORC1 (55, 130)