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These Phase 3 RCTs currently in progress and in the pipeline should provide further clarity on the long-term safety and overall effect of once-weekly subcutaneous retatrutide

More specifically, studies that delineate the effects of neuropeptides on submucosal gland secretion versus surface epithelial cell secretion need to be addressed

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The most interesting research involves NF-kB and MAPK signaling, PepT1-mediated intestinal uptake, colitis models, and targeted delivery systems for gut inflammation