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Mild nausea, fatigue, or digestive changes are the most common, especially when increasing the dose

For drug that is absorbed into the conjunctiva following topical application, only approximately 0.1% of the dose may reach the retina through transscleral diffusion after much of the drug is lost via systemic absorption through the conjunctival blood vessels [17,18,19]

Pacientes con gastroparesia preexistente, historia de enfermedad de vescula biliar o retinopata diabtica proliferativa deben ser evaluados cuidadosamente, ya que estos medicamentos pueden exacerbar estas condiciones

An insufficient supply of B vitamins, especially vitamin B12, leads to hair loss, according to a study