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The mechanism is not fully understood, but theories include: Changes in blood flow to the optic nerve Rapid weight loss affecting ocular circulation Metabolic changes affecting eye health Legal Development: Vision loss cases are being consolidated into a separate MDL (MDL 3163) also overseen by Judge Marston

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Tirzepatide for Weight Loss: What It Is and Who Its For Tirzepatide was approved by the FDA in 2022 for type 2 diabetes, and in 2023 for weight control for people with obesity or overweight and at least one weight-related condition (like high blood pressure or cholesterol)

The WGCNA approach, applied to this set of microarray data, clusters co-regulated genes based on their co-expression pattern and organizes them into modules. An eigengene score is thereafter applied to each module derived from the z-scored log 2-fold change values of the genes consisting the module (module membership)