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Getting that reaction at the site is exactly what we would expect a vaccine to do that is trying to mimic a pathogen without causing the disease, says Deborah Fuller, a vaccinologist at the University of Washington School of Medicine, in Seattle

at the same time, cash-pay options have emerged (e.g., Wegovy $499/month via NovoCare

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Monitoring and assessment Regardless of protocol, regular monitoring should include: Cognitive testing at baseline and regular intervals (MMSE, MoCA, or ADAS-cog) Vital signs during and after each administration session Hepatic and renal function panels (baseline and periodic) Neurological examination for seizure risk assessment Self-reported side effects diary Track progress using standardized scales