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Upon presentation, additional laboratory studies are necessary to obtain other important clinical parameters, including arterial blood gas (to investigate acid/base status), coagulation profile, basic metabolic panel, hepatic function tests, and urine drug screen (to determine possible co-ingestions)

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Any use would occur in the gray-market research chemical space, outside regulatory protections and medical oversight

In contrast, the accumulation of P6C can react with PLP to form a Knoevenagel condensate, which inactivates PLP and interferes with the metabolism of important neurotransmitters in the brain (Fig