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Tirzepatide: a Targeted Advancement in OSA Management Among metabolic therapies, tirzepatide has generated particular interest and emerged as the most clinically advanced agent in this class owing to its dual mechanism of action

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Dosing: Daily subcutaneous injection Maximum dose: 3.0 mg/day Average weight loss (SCALE trial): 8% over 56 weeks List price: ~$1,349/mo FDA-approved for: Adults and adolescents 12+ with BMI 30 (or 27 with comorbidities) Zepbound (Tirzepatide) The 2023 Newcomer Zepbound, FDA-approved in November 2023, contains tirzepatide a dual GIP/GLP-1 receptor agonist

PubMed, Miglis, Mitchell G., et al