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If large MPNSTs occur in nerves adjacent to major arteries, such as the brachial plexus or femoral nerve, they require amputation at a higher level for radical resection

investigated the role of chronic AMPK activation by metformin in restoring cardiomyocyte autophagy in OVE26 diabetic mice, a model for type one diabetes (231)

Sikiric, P., Seiwerth, S., Rucman, R., Turkovic, B., Rokotov, D

In support of the carnosine shuttle hypothesis, recent data in cardiac myocytes has demonstrated that carnosine is not just a buffer, but is also involved in Ca 2+ and H + handling from the sarcoplasmic reticulum as a type of carnosine shuttle (Figure 1