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During the 30-week double-blind placebo-controlled period of the glycemic control trial in pediatric patients 10 years of age or older with type 2 diabetes mellitus [see Clinical Studies (14.5)], 30/61 (49%) of MOUNJARO-treated pediatric patients developed anti-tirzepatide antibodies

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Testing revealed that the intra-assay coefficient of variation for the PAI-1 antigen ranged from 3.6-16.9% and the inter-assay coefficient of variation was 4.3-6.8%

in fact, it's a side effect that's been documented with other vaccines, antibiotics and pain medicines