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This study systematically explored the associations between GLP-1RAs and 12 common psychiatric and neurodevelopmental conditions using large-scale GWAS datasets, revealing protective effects against schizophrenia, anxiety disorders, bipolar disorder, bulimia nervosa, PTSD, and autism, with consistent findings across multiple databases for anxiety disorders, autism, and schizophrenia

IMC also prevented diet-driven hepatic cholesterol accumulation and caused both upregulation of the host hepatic bile acid synthetic enzyme CYP7A1 and altered the expression of hepatic genes critical for bile acid feedback regulation

Here, LC, functioning as an essential cofactor and metabolic regulator, directly counteracts core pathological processes by enhancing mitochondrial -oxidation and attenuating oxidative stress