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5.5 Observational and Mechanistic Literature Mechanistic literature suggests several plausible pathways for nutritional vulnerability: Reduced food volume Reduced dietary fat affecting fat-soluble vitamin absorption Reduced red meat intake affecting iron and B12 intake Reduced whole-grain intake affecting magnesium intake However: Plausibility proven clinical depletion

In the hippocampus, tyrosol reduced oxidative stress markers (ROS and MDA) and enhanced activities of antioxidant enzymes (GPX and SOD) in PMD rats

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