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Recent studies of the spatial organization of mucin-producing cells have led to new understanding of the difference between constitutive MUC5B production by superficial epithelial cells and between trigger-induced production and secretion by the goblet cells and submucosal glands

This diversity enables phenotypic switching and escape from single-target approaches

For example, in colorectal cancer, CD44 is broadly expressed across both CSC and non-CSC populations, leading to inconsistent results in CSC isolation

Effects of propolis, royal jelly, honey and bee pollen on growth performance and immune system of Japanese quails