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By activating GLP-1 receptors in the brain, semaglutide helps to increase the production of satiety hormones and reduce hunger signals, making it easier for individuals to adhere to a healthy eating plan

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Steitz et al 6 reported that VSMCs undergo a phenotypic transition into osteoblast-like cells in response to mineralization, evidenced by an increase in the expression of ALP, osteocalcin, Cbfa1 and osteopontin