glp 1 water intake Endogenous Glucagon-Like Peptide-1 Reduces Drinking Behavior and Is Differentially Engaged by and Food Intakes in Rats Electrolytes 101: The Guide for

That's the labeled titration protocol designed to minimize gastrointestinal side effects while your body adjusts

This is not necessarily a negative side effect but rather an indication of accelerated cell turnover, where underlying congestion is brought to the surface as the skin rapidly sheds old cells and regenerates new ones

According to the leaky gut theory, these alterations in gut microbiota may be related to inadequate perfusion to the viscera due to cardiac congestion or impaired ejection capacity in patients with HF, and ischemic edema in the intestine caused by ischemia, which might increase the permeability of the intestinal epithelium (Sandek et al., 2007), thus allowing intestinal macrobiotic and bacterial metabolites to gain access to the circulatory system through the compromised barrier

For me, this is usually a combination of a patients symptoms and risk factors