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NRF2 immunobiology in cancer: implications for immunotherapy and therapeutic targeting

Combined treatment with anti-IGF-IR agents and SFK inhibitors enhances antitumor activity [173]

For instance, bone marrow MSC-derived exosomes (BMSC-Exos) downregulate METTL3 expression, disrupt the m6A-mediated stabilization of ACSL4 mRNA, and ultimately reduce intracellular Fe + , ROS, and lipid peroxidation

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