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Description

Therefore, clonidine therapy must always be tapered gradually over a minimum of 2 to 4 days (or weeks for higher doses), and any concurrent beta-blockers must be discontinued several days prior to beginning the taper (JAVADIN, 2025

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On the other hand, clinical studies found an increased risk of bleeding disturbances with pills containing 20 mcg of ethinyl estradiol compared to pills containing more than 20 mcg of ethinyl estradiol

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Systemic side effects are not well-documented in human studies at therapeutic doses

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