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Medically reviewed by Miyuki Abe, Pharmacist July 26, 2026 Highlights Key takeaways 01 Aim for 2 to 3 liters of total fluid a day as a default, counting water, sparkling water, tea, coffee, broth, and watery foods

Retatrutide Phase 2 (Jastreboff et al., NEJM 2023) reported 24.2% weight loss at 48 weeks at 12 mg

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